Miran Skrap

 

Personal details

Born in Trieste (Italy)  20.8.53,

Italian nationality

Corresponding address: Azienda ospedaliero-universitaria di Udine

Pzz.a Santa Maria della Misericordia 1

Udine – Italia

Tel:+39-0432-552701

Fax:+39-043-2552700

Email.skrap@aoud.sanita.fvg.it

 

Personal statement

Chairman of Neurosurgical Department     of the  Azienda Ospedaliera-Universitaria  SMM –Udine-Italy

Elected member  (Past) of the Council of  the  Italian Neurosurgical Society (SINch)

Leading Italian neurosurgeon in low grade gliomas and awake craniotomies and particular interest in functional neurosurgery.

Co / Author of 74  publications (in PUBMED)

Collaborator in several research projects in neuro-oncological and neuro functional field.

 

Education and qualifications

Graduated at the   Medical school  in  Trieste on 17.7.78 

Assistant  at the Neurosurgical Dept . in Lubljana (Slovenija)   from 15.3.1979 to 18.8.81 and from  1.8.1982  to   15.1.84.

Graduated   in Neurosurgery   in   Padova   on  1988

Senior assistant   at the Neurosurgical Dept.   of  Trieste from  7.7.1990  

Chairman    of Neurosurgery in   Udine  from  25.11.1997

 

Clinical skills and experience

All neurosurgical onco-vascular procedures with particular interest in low grade gliomas with functional elaborations and awake craniotomies. 

Courses and conferences

Assistant at the Neurosurgical Dept.   of the University in Ljubljana  from  15.3.1979 till  18.8.81 and from  1.8.1982  till  15.1.84.(4 years with prof.V.Dolenc) . From  1985 several stages  by M.G.Yasargil (Zurich-Switzerland, T.Sundt (Mayo  Clinic-USA), C.Wilson (Univ.of San Francisco-USA), P.Jannetta (Univ.of Pttsburgh-USA), P.Kelly (Mayo  Clinic-USA), G.Ojemann (Washington Univ.Seattle)  P.Kelly (NYU Medical Center-USA) New York

Large number of talks as invited speaker at Italian and international level.

Organizer and president of  the following congresses

National congress of the Italian society of neurosurgeons, neurologist and neuroradiologist. SNO  (Societa’ Italiana di Neurologi,Neurochirurghi e Neuroradiologi Ospedalieri)

Grado 2004

National Congress of the Italian neurosurgical Society  I   and Joint meeting with Japan Neurosurgical Society.

Udine  2008

International  meeting:”Cerebral functions and surgery”

Udine 2011

 

Research experience

 

Projects  with:

SISSA Scuola Internazionale Superiore di Studi Avanzati di Trieste

Neuropsychologial testing in brain tumor patients and brain mapping.

 

l’IRCS Istituto Medea “Nostra Famiglia” (Conegliano Veneto)   

Program on dystonia and epilepsy in pediatric patients

 

l’IRCS Istituto Medea “Nostra Famiglia” (Udine)

Functional 3Tesla MRI in tumoral patients

 

Universita’ di Ferrara , Istituto di Fisiologia Umana

Cortical microrecording in peritumoral critical  brain areas.

 

Ist.di Anatomia Patologica Univ.Udine .

Human Low Grade Glioma Cultures and molecular analysis

CRO Aviano:

Somatic germinal mutations in patients with glioblastoma

Low Grade Glioma european network  

Low grade gliomas and therapeutic strategy     

 

 lTI   (Ist.Tecnologico Italiano) di Genova .

   “Brain machine interface” project

 

European Program Inter-Reg 2012

Cerebral gliomas and molecular factors.

 

Department of Biochemistry and Molecular Biology

Edward A. Doisy Research Center. Saint Louis University School of Medicine

Proteomic studies on low grade gliomas.

 

Teaching experience

 

Teaching at the Neurosurgical School of the Medical School in Padova and Neaples, at the General Surgery   and Ophthalmology School of the Medical school in Udine.

Organizer of regular yearly  courses of brain mapping in Udine.

 

Publications 2014-2015

1-A compact and autoclavable system for acute extracellular neural recording and brain pressure monitoring for humans.

Angotzi GN, Baranauskas G, Vato A, Bonfanti A, Zambra G, Maggiolini E, Semprini M, Ricci D, Ansaldo A, Castagnola E, Ius T, Skrap M, Fadiga L.

IEEE Trans Biomed Circuits Syst. 2015 Feb;9(1):50-9

 

2-Investigation of adhesion and mechanical properties of human glioma cells by single cell force spectroscopy and atomic force microscopy. Andolfi L, Bourkoula E, Migliorini E, Palma A, Pucer A, Skrap M, Scoles G, Beltrami AP, Cesselli D, Lazzarino M.

PLoS One. 2014 Nov 12;9(11):

 

3-Alterations in fiber pathways reveal brain tumor typology: a diffusion tractography study.

Campanella M, Ius T, Skrap M, Fadiga L.

PeerJ. 2014 Sep 9;2:

 

4-Involuntary switching into the native language induced by electrocortical stimulation of the superior temporal gyrus: a multimodal mapping study.

Tomasino B, Marin D, Canderan C, Maieron M, Budai R, Fabbro F, Skrap M.

Neuropsychologia. 2014 Sep;62:87-100.

 

5-Clinical outcome of deep brain stimulation for dystonia: constant-current or constant-voltage stimulation? A non-randomized study.

Lettieri C, Rinaldo S, Devigili G, Pisa F, Mucchiut M, Belgrado E, Mondani M, D'Auria S, Ius T, Skrap M, Eleopra R.

Eur J Neurol. 2014 Jul 10.

 

6-Impact of brain tumour location on emotion and personality: a voxel-based lesion symptom mapping study on mentalization processes.

Campanella F, Shallice T, Ius T, Fabbro F, Skrap M

Brain. 2014 Sep;137(Pt 9):2532-45.

 

7-To move or not to move: Subthalamic deep brain stimulation effects on implicit motor simulation.

Tomasino B, Marin D, Eleopra R, Rinaldo S, Cristian L, Marco M, Enrico B, Zanier M, Budai R, Mondani M, D'Auria S, Skrap M, Fabbro F.

Brain Res. 2014 Jun 13

 

8-Smaller, softer, lower-impedance electrodes for human neuroprosthesis: a pragmatic approach.

Castagnola E, Ansaldo A, Maggiolini E, Ius T, Skrap M, Ricci D, Fadiga L.

Front Neuroeng. 2014 Apr 16;7:8.

 

9-.Microsubthalamotomy improves sleep in patients affected by advanced Parkinson's disease.

Merlino G, Lettieri C, Mondani M, Belgrado E, Devigili G, Mucchiut M, Rinaldo S, Craighero C, D'Auria S, Skrap M, Eleopra R.

Sleep Med. 2014 Jun;15(6):637-41.

 

10-Glioma-associated stem cells: a novel class of tumor-supporting cells able to predict prognosis of human low-grade gliomas.

5.Bourkoula E, Mangoni D, Ius T, Pucer A, Isola M, Musiello D, Marzinotto S, Toffoletto B, Sorrentino M, Palma A, Caponnetto F, Gregoraci G, Vindigni M, Pizzolitto S, Falconieri G, De Maglio G, Pecile V, Ruaro ME, Gri G, Parisse P, Casalis L, Scoles G, Skrap M, Beltrami CA, Beltrami AP, Cesselli D.

Stem Cells. 2014 May;32(5):1239-53.

 

11-Surgery for insular low-grade glioma: predictors of postoperative seizure outcome.

Ius T, Pauletto G, Isola M, Gregoraci G, Budai R, Lettieri C, Eleopra R, Fadiga L, Skrap M.

J Neurosurg. 2014 Jan;120(1):12-23